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The disease occurs when these cells slowly start to die off : Fuchs' endothelial dystrophy is a non-inflammatory, sporadic or autosomal dominant, dystrophy involving the endothelial layer of the cornea
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Source: godthotslfc.pages.dev 0fe1 9a05 Fecd 2024 7d214 Belita Josefina , 25, 49 In vitro FECD models showed that FECD cells rapidly deposit high amounts of fibronectin on the surface of their basement membrane. FECD-related genes include TCF4, COL8A2, ZEB1, AGBL1, SLC4A11, DMPK, LOXHD1, LAMC1, ATP1B1, and KANK4 [42] [43] [44], and environmental factors (especially UVA) also play an important role [45.
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2025 年新年贺卡 免费图片 Public Domain Pictures . Click here to read the latest clinical management guidelines for corneal dystrophy Finally, RNASeq evaluation of RNA samples from the corneal epithelia of a FECD-affected and an unaffected subject confirmed target tissue expression of both DMPK and TCF4